منابع مشابه
Genetic Testing in Male Infertility
Infertility is a major health problem which affects approximately 22% of married couples in reproductive age. The apparent increased incidence of male infertility, in parallel with the widespread use of in vitro fertilization (IVF), raises concern as to the impact of advanced assisted conception techniques in transmitting genetic anomalies to the offspring. Recent research has widely focused on...
متن کاملGenetic Causes of Male Infertility
Infertility is a major health problem today, affecting about 15.0% of couples trying to have a child. Impaired fertility of the male is causative in 20.0% of infertile couples and contributory in up to another 30.0-40.0%. Infertility already affects about 5.0-7.0% of the general male population and may further increase in the future, considering the apparent trend of declining sperm count in in...
متن کاملGenetic evaluation of male infertility
Men with severe oligospermia (<5 million sperm/mL ejaculate fluid) or azoospermia should receive genetic testing to clarify etiology of male infertility prior to treatment. Categorization by obstructive azoospermia (OA) or non-obstructive azoospermia (NOA) is critical since genetic testing differs for the former with normal testicular function, testicular volume (~20 mL), and follicle-stimulati...
متن کاملGenetic Variation of Choline Dehydrogenase Gene in Idiopathic Male Infertility
Infertility can be caused by an unexplained reduction in semen quality in males who present asnormal on physical examination and endocrine testing. There is some evidence that aberrantmetabolism of micronutrients such as choline may play a causative role in male factorinfertility. Choline is a crucial factor in the regulation of sperm membrane structure andmotility, and this nutrient plays an i...
متن کاملUnexplained male infertility: diagnosis and management.
Unexplained male infertility is a diagnosis reserved for men in whom routine semen analyses results are within normal values and physical as well as endocrine abnormalities were ruled out. In addition to erectile problems and coital factors, immunologic causes and sperm dysfunction may contribute to such condition. New etiologies of unexplained male infertility include low level leukocytospermi...
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ژورنال
عنوان ژورنال: Urological Science
سال: 2010
ISSN: 1879-5226
DOI: 10.1016/s1879-5226(10)60016-4